Researchers are investigating the potential risks associated with Ozempic. Dr. Mahyar Zasat from the University of British Columbia says that significant cases of the connection between the use of this drug and suicidal thoughts have been seen in patients.
According to RCO News Agency, For some time, the drug Ozempic, an injectable prescription drug that effectively treats type 2 diabetes, has gained popularity due to its weight loss claims. Meanwhile, some patients have reported suicidal thoughts after taking this injectable drug.
This drug is basically based on a semaglutide molecule that mimics the structure of glucagon-like peptide-1 (GLP-1), a human hormone that regulates appetite and sugar levels by using specific receptors in these channels. Blood helps.
Due to similar structures, semaglutide can help to feel full, make people less hungry, and also prevent people from overeating.
Semaglutide was very popular between 2020 and 2022, and its prescription and use increased by more than 300% in the United States, but the problem started when people started using the drug solely as a weight loss drug, which had its own side effects. had the
Evidence of ozmpic association with suicidal ideation
Now a new study has linked Ozemic to increased suicidal thoughts, but researchers remain cautious about that.
According to the researchers, many patients have reported intestinal problems after taking this drug, and of course, in psychiatric studies, an increase in suicidal thoughts has also been reported.
A new study published in the journal JAMA Network Open reported that patients who took semaglutide had suicidal thoughts. The researchers found 107 reports from patients, about 30,500 of whom said they wanted to kill themselves while taking the drug.
Additionally, about 52,000 people taking the older diabetes drug liraglutide did not report this. However, when the researchers compared reports of suicidal thoughts with previous medication, they found that the risk increased by about 45 percent.
They even suggested that this group of people is about four times more at risk than their peers.
Dr. Mehyar Tsatsat, a drug safety expert at the University of British Columbia, says: “Basically, it is difficult to know from this study whether this drug does this or whether it is the mood disorder that causes it.”
It should be said that researchers are still debating whether or not this study is accurate and have stated that this study has its own limitations.
“This paper provides weak evidence at best of a link between semaglutide and suicide,” said researcher Ian Douglas.
Advise caution in using Ozempic
As the debate continues about the possible psychiatric risks of Ozempic, experts recommend caution in its use.
Despite all the reactions of the medical community, many doctors agree with this connection. They believe that this drug is a common drug and, in most cases, conclusions about it may differ depending on the database used or the methods used to conduct the research.
Two French doctors named Francesco Salvo and Jean-Luc Filey say: Depression or suicide are rare but very severe events and should be prevented and managed as much as possible.
For now, more information and more research is needed to find out if these claims are true or not. Although there is strong evidence supporting the negative side effects of this drug, there are still some gray areas.
For example, there is a whole group of researchers who do not agree with this study at all.
Ultimately, doctors say that with all of this in mind, if patients taking Ozempic experience any discomfort at any time, they should stop taking the drug immediately.
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