According to RCO News Agency, according to the University of Tehran, in the form of a post -research research by Ali Ghorbani Ranjbari, the University of Tehran Veterinary Safety Researcher, with the guidance of Dr. Jalil Mehrzad, Professor of Microbiology and Immunology of Tehran University of Veterinary Medicine, and Dr. Hussam Dehghani, Professor of Ferdowsi University. In the blood and metaphor of cancer tumors, with the induction of apoptosis and the inhibition of metastasis molecules, it can be effective in the immune therapy of colon cancer (CRC).
Dr. Mehrzad, the head of the study, said of the need to conduct the study, “The colon cancer as the third leading cause of cancer -induced death in the world, especially in young people, is experiencing a worrying increase and the need to discover modern molecular mechanisms to inhibit the growth and metastasis of the cancer.”
“This interdependent study has examined the role of cytokine interlukin -2 in the destruction of cancer cells and the immune therapy of colon cancer and has led to very promising results,” said a professor of safety in the Faculty of Veterinary Medicine at the University of Tehran. A six-year study of four patients with colon cancer showed that IL-1 results in the control of apoptosis and autophagic proteins, leading to the exacerbation of apoptosis (planned death) and ultimately disappearing of cancer cells. “
“In addition, IL-1 has a molecule molecule (B۲Gatn۲), often has an impact effect and can control the process of expanding colon cancer cells in the body,” said Dr. Mehrzad.
The professor at the University of Tehran also pointed to the methods used in this study, saying, “In this study, the use of new technologies such as Western Blatt, Luminometrometry, Flusometriometry and Electron Microscopic Cancer Cell Cells were analyzed.”
“This is the first scientific report to show that the timely increase of IL-1 not only induces apoptosis in colon cancer cells, but also paves the way for the design of hybrid immune drugs by inhibiting metastasis,” the head of the study emphasized.
“The future focus of this research team will be on the design of smart nanostructures to deliver this cytokine to the cancer,” said a professor at the University of Tehran Veterinary Medicine.
The findings of this study are published as Impact of IL-1A on Apoptosis and Mucinosis-Related Molecles in the Microenvironment of Colorectal Cancer in the reputable journal of Medical Research.
(tagstotranslate) Immunology (T) University of Tehran (T) Colon Cancer (T) Scientific Research (T) Iranian Universities (T) Cancer
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