As the opiate crisis continues, the number of infants born with neonatal opiates (NOWS) is a condition that affects infants whose mothers used opiates during pregnancy has increased by five times in the last five years. These babies often need to be hospitalized for prolonged hospitalization and in some cases, treating medications such as morphine to relieve symptoms.
According to RCO News Agency, A new study by Dr. Walter Kraft, an internal specialist and clinical pharmacist at Thomas Jefferson University and his group, is the potential of ondanSetron, a drug commonly used to treat nausea and considered safe during pregnancy, to help reduce symptoms of abandonment in infants.
According to the Medical Express, the study, according to Dr. Kraft’s previous research data, along with his colleagues at Stanford University, extended from a clinical trial in Jefferson and other centers. That study examined the impact of Andanastrone in four infants and found that it significantly reduced the severity of the cracked symptoms.
Arbitrary use of any medication without a doctor’s prescription can have irreparable side effects, and researchers recommend that you see a specialist physician to follow up.
In the current study, led by Kevin Lam, a mathematical method that describes how the drug is processed by different patients was used to identify the concentration of Andanosterone that leads to the relief of symptoms. This model can be used to simulate optimum doses of Andanastron.
“In the past, we might use internal intuition and say, let’s just double the dose, but now we can use mathematical modeling to get more likely to find an effective dose and need less patients to enroll in a clinical trial,” says Dr. Craft.
Dr. Craft, who is also a faculty member of Sydney Kimel Medical College, says his group is looking for a budget for future clinical trials to investigate whether Andanteron can reduce the number of symptoms experienced by infants with this condition or shorten their stay in the hospital.
“This is a complex medical and social issue,” said Dr. Craft. There is unlikely to have a single solution. We are optimistic that onsetone may be part of a multilateral approach to improving the care of these babies.
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