The Secret of Middle Ages Obesity Disclosed – | Iranian and world news

Everyone knows that as people pass through their waist and abdomen, they are not just a beauty problem, according to . Abdominal fat accelerates aging and reduces body metabolism. In addition, this type of fat increases the risk of diabetes and other chronic diseases, although the reason why the abdomen collects fat in middle age has been ambiguous.

Now, during the pre -clinical research of the Institute of Research, City Avope has discovered age -related abdominal obesity cells, and a new perspective on the middle part of the body has been widened.

These findings show a new goal for treatments that prevent abdominal fat and extend human health. “Most of the time when they are elderly, although their weight remains constant, the muscle lose India and adds fat,” says Kyung Wang, a researcher. We found that aging leads to a new type of adult stem cells into the body, which adds mass production of fat cells, especially around the abdomen.

Researchers, in collaboration with Xia Young of UCLA University, conducted tests on mice, the results of which were later confirmed on human cells. Wang and his colleagues focused on white adipose tissue, which is the reason for age -related overweight. Fat cells grow older, and the researchers estimate that this type of tissue is expanded by the production of new fat cells. This means that white adipose tissue has an unlimited potential for growth.

Researchers focused on fat prehental cells (APCs) to test their hypothesis.

The City City Hope team has transplanted the old young mice APCs in a group of young rats. Older animal fat precursor cells were rapidly produced and made a lot of fat. When the APC team transplanted young mice in the old, stem cells could not create a large number of fresh fat cells.

These results show that older APCs are equipped so that they can be made independently and regardless of the age of the host new fat cells.

Next, the researchers compared the APC gene activity in young and older mice using a single -celled RNA sequence. Although APCs are rarely active in young mice, they have been activated in mid -year mice and led to the pumping of new fat cells.