Researchers: Coordination between the body’s internal clock in the brain and liver is related to obesity

A new study has shown that coordination between the body’s internal clock in the brain and liver is very important. Disruption of this coordination can lead to problems such as overeating and weight gain.

According to the scientific news department of Tekna Technology Media, there is an internal clock in our body that helps us regulate sleep and wake cycles, food digestion and other body activities. This clock is located in a part of the brain called the suprachiasmatic nucleus (SCN). The SCN regulates the body’s circadian rhythm by receiving light signals from the eye. In addition to the SCN, almost all cells in the body, including liver cells, have their own internal clock. The liver’s internal clock is mostly influenced by dietary patterns.

In order for the body to function properly, the internal clock of the brain and liver must be in sync. When this harmony is disrupted, for example due to shift work or long journeys, health problems such as obesity, diabetes and heart disease increase. Researchers in this study, by changing the internal clock of the liver of mice, concluded that disruption of the liver clock can cause overeating and weight gain. These mice ate more when they should have rested.

The hepatic afferent vagus nerve establishes a connection between the brain and the liver. Researchers found that cutting off this nerve can prevent overeating caused by a disruption in the liver clock. This study shows that the connection between brain and liver is very important in regulating eating behaviors. Disruption of this relationship can lead to obesity and other health problems. By better understanding this mechanism, we can find new ways to treat obesity and metabolic disorders. To see the latest news, refer to the scientific news page of Tekna Media.