If you want to know High anti-tpo in blood test What are the signs in men and women, follow this article to the end.
High anti-tpo in blood test
A high level of anti-tpo in blood tests in men and women is a sign of autoimmunity in the body. Thyroid peroxidase (TPO) antibodies are a type of thyroid antibody. Thyroid antibodies can form in autoimmune thyroid disease. The body mistakenly recognizes thyroid cells and tissues as non-self. This means that our body sees its own cells and tissues as foreign and attacks them.
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What is anti tpo in blood test?
anti tpo blood test is a medical test used to detect TPO antibodies in your blood. TPO stands for thyroid peroxidase, which is an enzyme produced by the thyroid gland, which is located at the base of your neck, just below the Adam’s apple. The butterfly-shaped thyroid gland produces thyroid hormones, which play an important role in regulating and maintaining your body temperature, body weight, growth, development, and muscle strength. This test, also known as a thyroid peroxidase autoantibody test, checks for levels of thyroid antibodies in your body that can indicate serious medical conditions.
What is the sign of high anti tpo?
If the level of antibodies in your body is less than 9 IU/mL, the TPO antibody level is considered normal and there is nothing to worry about. But high anti tpo is a sign of problem.
Studies show that a combination of factors such as certain drug use, exposure to infection, high iodine levels, pregnancy, and family history may contribute to high levels of anti-TPO antibodies in your body. Research studies also show that women have a higher risk of developing autoimmune thyroid disorders than men.
What factors cause anti tpo to rise?
Among the factors that cause the increase of anti-tpo, we can mention thyroid autoimmune disorders that lead to an increase in thyroid peroxidase antibodies. The two main autoimmune thyroid disorders are Grave’s disease and Hashimoto’s thyroiditis
Anti-TPO antibodies are present in:
- 80-95% of cases of Hashimoto’s thyroiditis
- 65-80% of cases of Grave’s disease
- 10-20% of thyroid cancer cases
- 10 to 15 percent of people who do not have any thyroid disorder can have elevated TPO antibodies. Elevated TPO antibodies may increase the risk of developing thyroid disorders in the future.
- Also, numerous research studies have shown that physical and mental stress can play a role in the development of autoimmune thyroid diseases such as Graves’ disease and Hashimoto’s disease.
Normal level of anti tpo in women and men
The normal level of anti-tpo in men and women is less than 30 international units per millimeter (IU/ml). Numbers higher than this value are high thyroid peroxidase antibodies. Note that the normal range of anti tpo can be different in different laboratories.
Symptoms of high anti tpo
Symptoms of high anti tpo can include the following:
- Fatigue, lethargy and sleepiness.
- Slight weight gain.
- constipation
- dry skin .
- Feeling cold.
- Heart rate slower than normal (bradycardia).
- Joint stiffness and muscle pain.
- dry and brittle hair; slow hair growth; or hair loss
- Low or depressed mood.
- Puffy eyes and face.
- Memory problems or difficulty concentrating.
- Heavy or irregular periods.
- Decreased libido (sexual desire).
- Female infertility or male infertility.
However, some people with high Anti-TPO levels may remain asymptomatic and have no symptoms at all. If you notice any of these symptoms, consult your doctor for proper evaluation and treatment.
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Is high TPO dangerous?
High anti-TPO is dangerous when the body’s immune system acts against the thyroid gland (such as autoimmune thyroid diseases) and may increase the risk of recurrent miscarriage, premature birth, and thyroid dysfunction after delivery. However, there is no need to worry as this condition can be controlled.
What are the complications of high tpo?
The side effects of high tpo may be seen in the following ways, although not all cases occur in the same person:
- heart problems
- Complications related to mental health such as depression
- sexual disorders
- Disorders related to the reproductive system
- I bite
The presence of TPO antibodies during pregnancy is associated with increased rates of complications such as placental abruption, gestational hypertension, preterm labor, miscarriage, and postpartum thyroid disease, even when thyroid function is normal.
If the rise of Anti TPO is due to Graves, the following complications may also be observed in the patient:
- Graves’ eye disease, which appears as an abnormal protrusion of the eye
- Graves’ dermopathy is a skin disease
- Thyroid storm, which is one of its most fatal complications
- Heart disease
- Osteoporosis
Treatment of high anti tpo
Diet, lifestyle, supplements and herbs are the cornerstones of treating any autoimmune disease. It may also be necessary to supplement with biosimilar hormones and low-dose medications.
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To treat high anti-tpo levels, you must do the following:
1. Adequate intake of nutrients
In order to treat high anti-tpo levels, essential nutrients must be consumed in sufficient quantities to maintain thyroid function and the proper functioning of the immune system. Among these nutrients are:
- Vitamin D
- Selenium
- B group vitamins
- Zink
- magnesium
- iron
Follow a nutrient-dense autoimmune protocol (AIP) diet, and it’s important to avoid gluten and dairy. This diet supports healthy intestinal flora and is rich in anti-inflammatory nutrients.
2. Stress control
Different techniques, including meditation and fast breathing with 5 seconds of inhaling and exhaling, are suitable ways to reduce stress and help the immune system function properly.
3. Physical activity
Physical activity and exercise significantly increase the amount of regulatory T cells. As their name suggests, their job is to regulate the functioning of the immune system. These cells are responsible for maintaining the balance and preventing the growth of autoimmune cells; As a result, exercise is effective in dealing with autoimmunity and reducing harmful antibodies.
4. Stay away from toxins
In today’s life, we are constantly exposed to toxins. But there are things you can do to reduce exposure to toxins, including:
- Use a high-quality water filter
- Eat organic products as much as possible
- Avoid processed foods
- Avoid drinking or eating from plastic containers
- To prevent substances and chemical pollution from entering the house, remove the shoes before entering the house.
- Dust the interior of the house regularly. Heavy metals and other chemicals are transported along with dust particles.
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