With a new method, researchers managed to transform skin cells into eggs that can be used to create healthy embryos.
According to Tekna technology and technology news service, researchers at Oregon Health and Science University unveiled a new approach with the ability to treat infertility. These researchers were able to create laboratory gametogenesis in a mouse model. This gametogenesis was created by the fusion of the nucleus of the skin cell with the egg.
Mitalipov, the director of the center of this university and the senior author of this study, says: This method will produce eggs for patients who lack eggs. In this method, researchers used somatic cell nucleus transfer. This method places the skin cell nucleus in a donor egg, which generally has no nucleus. This method along with a set of advanced biological steps was tested on a mouse. Finally, the researchers succeeded in creating embryos with chromosomes received from both parents. This method is similar to normal meiosis where mature sperm or egg cells are created through cell division. Then, the new egg is fertilized with sperm in the experimental fertilization process. According to the researchers, this process was able to produce healthy children with equal genetic contribution from both parents.
According to the researchers, one of the advantages of using this method is to avoid the long period of cultivation, which considers cell reprogramming as necessary. These researchers are trying to use this innovative method on human eggs and early embryos and investigate this technology. But it will probably take several years for the clinical use of this method.
Women who are of advanced maternal age or who are unable to produce live eggs as a result of cancer treatment can use this advanced method in the future.
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