Only 24 hours of insomnia, the main spark of obesity

According to RCO News AgencyAccording to new research, not sleeping only for one night causes healthy adults to see increased immune cells associated with chronic inflammation, which is one of the key features of obesity.

The good news is that when normal sleep is restored, everything goes back to normal.

According to the New Atlantic, this points to the strong relationship between sleep and the health of the immune system.

Scientists have long examined the relationship between sleep and weight. In recent years, it has been revealed that sleep regulation is not only related to the brain, but also depends on the complex interaction between the brain and the rest of the body. While the effect of sleep deprivation on health is known, the infrastructure mechanism of this relationship is less known.

In new research, the Dasman Diabetes Institute (DDI) in Kuwait examined even a short period of sleep deprivation on the immune system of healthy people and how it affects the risk of diseases such as obesity, diabetes and heart disease.

“Our findings emphasize the growing challenge of public health,” said Dr. Fatemeh al-Rashd, a researcher at the DDI immunology and microbiology department, the supervisor and author of the study. Progress in technology, long time exposure to displays, and changing social norms increasingly disrupt regular sleep hours, and this sleep disorder has profound consequences on the health of the immune system and overall health.

The researchers selected 237 healthy adults with normal liver, heart, lung and kidney function. Then people with diabetes diagnosed by a physician, obstructive sleep apnea (OSA), hypertension, or those who use hypertension. Like those who had a history of significant heart problems such as heart attack, coronary artery transplant surgery, coronary artery angioplasty, or stent, or a family history of premature death (before age 40) for heart causes.

In addition, people with depression diagnosed or taking drugs that affect the quality of sleep or body weight were eliminated from this study.

Participants were divided into three groups of lean, overweight and obese according to BMI. The obese group was mostly divided into people with low, medium and high -risk obesity. To track activity and sleep, participants were asked to install an accelerator on their hip for seven consecutive days except when bathing.

In order for the participants to remain in the study, the accelerator had to be used at least four nights, which is needed to determine precise patterns of sleep and wakefulness. Blood samples for measuring cytokines and camcines, which are signaling proteins that help regulate inflammation and immune activity, and monocytes, which are white blood cells that help fight infection and heal damage.

The researchers found that obese people were significantly lower quality of sleep than lean participants and had a higher degree of chronic inflammation. Overweight and obese participants also had a significant number of non -classic monocytes (NCM), which are subgroups of monocytes that act as immune surveillance cells. They also had high levels of pre -inflammatory cytokines.

The researchers then conducted a control test to investigate the interaction between sleep deprivation and immune cell dynamics. They woke up five people with normal weight (two men and three women) for 24 hours. They observed an acute and significant increase in NCM circulation levels, which returned to the original a few days later when normal sleep was restored.

Professor Si Ming Man, a immunologist at the John Curtin School of Medical Research in Australia, who did not participate in the study, says: “This is an interesting study that shows the findings that low -quality sleep increases inflammation.

“What is interesting to me is that increasing inflammation, which has significant health consequences, is reversible with good sleep,” he said. This means that we can offset our lost sleep throughout the week to make sure that we are not constant and chronic in this defective cycle, which increases the likelihood of type 2 diabetes and cancer.

Researchers say more research is needed to discover the mechanisms of sleep deficiency, monocytes and inflammation in obesity. In addition, they intend to evaluate interventions designed to improve sleep quality in obese people because of their ability to weaken the immune response and reduce inflammation.

“In the long run, our goal is to make this research highlights policies and strategies to highlight the vital role of sleep in public health, al -Rashid says. We anticipate workplace reforms and training campaigns to promote better sleep practices, especially for populations that are at risk of being deprived because of technical and occupational needs. Finally, this study can help reduce the burden of inflammatory diseases such as obesity, diabetes and cardiovascular disease.

This study is published in the journal Immunology.

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