The role of drinking milk in increasing the effect of oral medications

According to RCO News AgencyNew research shows that when the milk is combined with specific oral medications, the body’s absorption improves significantly.

This is the latest finding from a set of studies that shows that milk is a very effective vehicle for drug delivery.

Many of us know that milk is very valuable in the health and medical world. Over the years, we’ve read a lot about the impact and benefits of milk, but what has become increasingly clear to scientists is that the combination of milk with the drug makes it an effective drug supply system.

A new study led by researchers at the University of Monash found that the addition of human and cattle milk significantly improves the effectiveness of some oral medications. This is the newest finding from a set of studies in which researchers have examined milk as a means of improving drug transfer.

Professor Ben Boyd of the Monash Institute of Pharmaceutical Sciences (MIPS) and the author in charge of the study said: “We have been constantly showing a way through our research over the years in which some specific medications can with milk that can be tapped. Our body treats it like food and digests it, comes together, and through this process, milk and medicine are absorbed together, thereby increasing the effectiveness of the drug.

The term “bioavailability” refers to how much the drug actually reaches the bloodstream. “Oral Biology” is a biological revenue of drugs that are swallowed or enter the stomach in a different way and are affected by several factors, including stomach pH and small intestine, enzymes and metabolism in the gastrointestinal tract. Therefore, the key to maximizing bioavailability is a drug formulation that affects the body’s absorption, distribution and use.

Many drugs are weak and fat in terms of soluble water, and both create challenges for biological affairs. As you probably know, the human body, including the gastrointestinal tract, is mainly made up of water, so if a drug is not well dissolved in water, it will be incomplete in the bloodstream.

Some medications also need fat to dissolve and absorb properly. That is why the pharmacist may tell you to take some medications with food.

This is where milk is used. Due to the content of fat, milk products can be considered a lipid -based formula that can increase the solubility of fatty drugs.

Research has also shown that when weaker drugs are solubility with water with human milk or cow, milk digestion increases the solubility of the drug. In addition, milk is widely available, low -cost and generally tolerable.

For the present study, the researchers focused on neonates and clofazimine. It is traditionally used to treat leprosy and tuberculosis. However, it is recently used to treat cryptocuridiosis, which is a parasitic infection and one of the common causes of child mortality in poor and medium -sized countries.

Clafazimine is very fat and is limited if it is used orally. To deal with this challenge, manufacturers of this drug are put in a soft gel capsule that unfortunately infants cannot swallow capsules. Therefore, the researchers examined whether the composition of this drug with milk improves its “bioavailability”.

Finally, the researchers found that the bioavailability of clofazimin was significantly higher when prescribing with human and cattle milk, and showing a 5 % and 5 % increase, respectively.

Ellie Ponsonby-Tomas, a senior author of the study, said: “Poor solutions such as clofazimin are not well dissolved in the stomach after use, and therefore the production of appropriate age formulations that are both safe and effective are challenging.” We know from previous studies that the formulations used for infants with milk can help dissolve medications in the stomach, so we were excited to see if this is also the case with clofazimine administration.

The findings of this study confirm previous studies of researchers. It was in the year that one study found that the solubility of two anti -malaria drugs could be increased using milk. The study was published in the journal Molecular Pharmacyutics.

Also, other studies in the years of Prazicantel and 2 on cannabidiol showed that milk consumption along with these drugs increases their bioavailability.

However, there are still many things to do. Although this set of studies make it clear that the effectiveness of important drugs is increased by milk, there are practical barriers to overcome it, such as limited access to the refrigerator in poor countries and changes in milk quality.

The study is published in the journal Pharmacyutics and Biopharmaceutics.

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