Burning and inflammation of the vaginal area can be one of the common problems that women experience at different times of their lives. In addition to causing pain and discomfort, this condition can be caused by infection or skin sensitivity. This issue increases the importance of choosing the best ointment for vaginal burning; Because the product you use plays an important role in quickly relieving symptoms and preventing further inflammation. In this article from Digikala Mag, we will introduce you the most effective prescription and non-prescription ointments so that you can know the best treatment options according to the cause of the burning in this area and start the treatment process with more knowledge.
Comparison of the best ointments for vaginal burning
| Ointment | type | Main application | suitable for | how to use | Prescription / non-prescription |
| clobetasol | Strong corticosteroid | Reduce inflammation and itching | Inflammation caused by skin diseases | Local on the outer skin | a copy |
| Calendula | Herbal/anti-inflammatory | Reduce itching and superficial burning | Non-infectious irritations caused by contact or dryness | Localized on the external area | No prescription |
| Hydrocortisone | Weak corticosteroids | Mild inflammation control | Allergic reaction and mild dermatitis | Local on the outer skin | Without a prescription (in low concentration) |
| Diproclus | Combined (betamethasone + clotrimazole) | Inflammation control + fungus treatment | Inflammation with fungal infection | Local on the outer skin | a copy |
| Lidocaine | Local anesthetic | Reduce pain and burning | Irritation from dryness or infection | Topical according to the doctor’s order | a copy |
| alpha | Natural ingredients | Repair and regeneration of the skin | Dryness and superficial irritations | Localized on the external area | No prescription |
| A+D | Vitamin A and D | Reconstruction of the protective layer of the skin | Irritations caused by friction or detergents | Localized on the outer skin | No prescription |
| Zinc oxide | Protective and anti-inflammatory | Reducing inflammation caused by friction or burns | Urinary burns, friction, surface irritations | Local on the outer skin | No prescription |
| Triamcinolone | Moderate corticosteroid | Reduce inflammation | Inflammation of the external area of the vagina | Local on the outer skin | a copy |
| Clotrimazole | Antifungal | Treatment of fungal infection | Fungal infections of the vagina | Topically on the external area or with an applicator | Prescription / non-prescription (low concentration in pharmacies) |
| Topical estrogen | Hormonal | Increased moisture and mucus thickness | Dryness caused by hormone deficiency | Topical according to the doctor’s order | a copy |
| Clindamycin | Topical antibiotic | Treatment of bacterial infection | Vaginal bacterial infections | Topical on the external or internal area according to the doctor’s order | a copy |
The best ointment for vaginal burning
The issue that many women do not pay attention to when looking for the best ointment for external vaginal itching and burning is that this condition can have various causes. From fungal and bacterial infections to dry skin, allergies and hormonal changes; There are many factors behind this that must be considered before starting treatment. This problem is usually associated with a feeling of burning, itching and inflammation, and its timely treatment is very important to prevent further discomfort. According to the main cause of vaginal itching, experts prescribe antifungal, antibacterial, anti-inflammatory or even estrogenic ointments for patients, which we will introduce below.
Clobetazol ointment for vaginal irritation
In cases where inflammation and irritation of the vagina are caused by certain skin diseases or chronic inflammatory reactions, specialists prescribe clobetasol ointment to patients. This drug is a type of strong corticosteroids and by reducing the activity of the immune system in the application area, it reduces inflammation, redness and itching. This ointment is mostly used in the treatment of problems such as lichen sclerosus or other severe dermatitis around the vagina. Despite the high effect that clobetasol ointment has, it must be used according to the doctor’s prescription; Because its long-term or arbitrary use can cause thinning of the skin or increase the sensitivity of the area. This medicine is not suitable for the treatment of burning caused by fungal, bacterial or viral infections and should not be used without investigating the root cause of burning.
Positive points
- Rapid reduction of inflammation and redness of the vaginal area
- Reducing itching caused by dermatitis and chronic skin problems
- Suitable for severe skin problems such as lichen sclerosus
Negative points
- Long-term use may cause thinning of the skin
- It is only suitable for relieving inflammation
- It requires a doctor’s prescription
Calendula ointment for vaginal burning
When irritation or redness of the skin of the genital area is caused by non-biological factors such as shaving or contact with detergents, calendula ointment can help relieve it. This herbal product is prepared from marigold extract and has anti-inflammatory and healing properties. Calendula gradually reduces itching and burning by reducing surface inflammation of the skin and helping to regenerate cells. However, never forget that this ointment is suitable for cases where vaginal burning is caused by sensitivity or dryness of the skin and not fungal or bacterial infections. The light and non-greasy texture of calendula ointment makes it not feel heavy or sticky when in contact with the sensitive area of the vagina. Excessive use of this ointment usually does not cause any complications; But it is better to consult a doctor to use it during pregnancy or if there is an open wound. Calendula is a mild sedative, but it is not considered a medicinal treatment for the infection.
Positive points
- Anti-inflammatory and natural healing
- Reducing itching and burning caused by non-biological stimuli
- Light and non-greasy, suitable for sensitive skin
Negative points
- It is not used for fungal or bacterial infections
- It does not have a quick therapeutic effect and works gradually
- It may be necessary to consult a doctor in case of an open wound or pregnancy
55,000 Toman
Hydrocortisone ointment for vaginal irritation

Hydrocortisone ointment is one of the common treatments for inflammation and itching of the vaginal area caused by an allergic reaction or mild dermatitis. This drug is considered a weak corticosteroid and by reducing the activity of the immune system at the site of use, it controls redness, swelling and burning sensation. Due to the mildness of this ointment, experts sometimes prescribe it for sensitive areas of the body, including around the vagina. However, long-term use of hydrocortisone ointment without a doctor’s prescription may cause thinning of the skin or increase the likelihood of re-irritation. This medicine is not suitable for burns that have an infectious origin, because it reduces the inflammation but does not eliminate the main cause. Do not forget that hydrocortisone is an ointment for burning the external part of the vagina and should never be used for the internal area.
Positive points
- Reducing redness, swelling and burning caused by an allergic reaction or mild dermatitis
- Gentle and usable for sensitive areas
- Controlling external inflammation of the vaginal area
Negative points
- Not suitable for fungal or bacterial infections
- Long-term use without a doctor’s prescription may cause thinning of the skin
- Suitable for external use only
Diprocol ointment for vaginal burning
Diprocol ointment is a combination of betamethasone and clotrimazole, and for this reason, it has both antifungal and anti-inflammatory properties. This drug is usually prescribed in conditions where skin inflammation is accompanied by fungal infection, such as some cases of chronic inflammation around the vagina. Clotrimazole inhibits the fungi that cause itching and burning, and betamethasone reduces redness and irritation with its strong anti-inflammatory effect. Diprocol ointment has effective ingredients, but its arbitrary use may disrupt the microbial balance of the skin or temporarily hide the signs of infection. This ointment should be used only if the doctor has confirmed the presence of a fungal agent. The period of use of Diprocol ointment should be limited and according to the prescription, because long-term use of corticosteroids in sensitive areas can cause thinning of the skin.
Positive points
- It has antifungal and anti-inflammatory properties
- Simultaneous reduction of itching, burning and inflammation caused by fungal infection
- Effective in chronic skin infections around the vagina
Negative points
- Arbitrary consumption can disrupt the microbial balance of the skin
- The period of use should be short and under the supervision of a doctor
- Long-term use can cause thinning of the skin
Lidocaine ointment for vaginal burning
Sometimes the burning and pain in the vaginal area becomes so annoying that you can’t even do your daily tasks without worrying. In these cases, the best ointment for vaginal burning is lidocaine ointment, whose name sounds familiar to all of us. By inhibiting the transmission of nerve messages in the skin, this drug temporarily reduces the feeling of pain and burning and can be prescribed for cases such as irritation caused by infection or dryness of the mucous membrane. Lidocaine does not have a therapeutic effect on the main cause and only helps to relieve its symptoms, so it should not be used as a substitute for the main treatment. This ointment must be used under the supervision of a specialist doctor; Because if it is absorbed too much through the skin, a person may experience widespread anesthesia or systemic complications. Overall, this ointment is an option for short-term control of pain and irritation so that the patient can better tolerate the main treatments.
Positive points
- Quick relief of pain and burning
- Reducing sensitivity and discomfort in daily activities
- Effective in irritation caused by dryness or infection
Negative points
- It does not affect the main cause of burning
- Overdose can cause systemic side effects
- It is only suitable for short-term control of symptoms

45,000
42,000 Toman
Alpha ointment for vaginal burning
One of the other treatments suggested in response to the question of what ointment to use for vaginal burning is Alpha Ointment. This ointment is made on the basis of natural ingredients such as allantoin extract, honey and olive oil and has a restorative effect. This drug is mostly used to heal superficial wounds, inflammation and mild burns and can be soothing in cases where vaginal burning is caused by other stimuli or dry skin. Alpha ointment actually helps to reduce vaginal burning and itching by regenerating damaged cells and maintaining the skin’s natural moisture. Its light and herbal texture does not irritate the vaginal area more than it is. Before using Alpha Ointment, you should make sure that you are not allergic to its ingredients. This ointment is only suitable for the external area and not inside the vagina and should be used with complete hygiene. If you want to know what is the strongest antibiotic for urinary infection, read our article about this topic.
Positive points
- Repairing and regenerating damaged cells
- Reducing burning and itching caused by dryness and irritation of the skin
- Light and herbal, low risk for sensitive skin
Negative points
- It is only used for the external area of the vagina
- Not suitable for fungal or bacterial infections
- Caution should be used in case of allergy to ointment ingredients

350,000 Toman
AD ointment for vaginal burning
A D ointment (A+D) is a topical medicine that is produced from the combination of vitamins A and D and helps to reduce skin irritations. When vaginal irritation is caused by dryness, friction or the use of irritating detergents, this ointment can help restore the skin’s protective layer. Vitamin A plays a role in cell regeneration and vitamin D helps reduce inflammation in this area. Regular use of this ointment can reduce the feeling of burning and dryness. AD does not have antifungal or antibacterial properties and should not be used to treat infections. It is better to use this ointment only on the outer skin of the vagina that is well cleaned and to avoid its contact with the inside of the vagina. AD ointment is usually safe, but people with very sensitive skin should do a skin test before using it.
Positive points
- Rebuilding the skin’s protective layer with vitamins A and D
- Reducing dryness and irritation caused by friction or detergents
- Local and safe use for the outer skin
Negative points
- It has no antifungal or antibacterial effect
- It is only used for the external area of the vagina

56,200
24,550 Toman
Zinc oxide ointment for vaginal burning

Zinc oxide is one of those well-known compounds that are used to reduce inflammation caused by burns, urine burns, and surface irritations. If vaginal irritation is caused by friction, sweat or contact with chemicals, this ointment can prevent the development of inflammation by creating a protective layer on the skin. With its anti-inflammatory and mild drying properties, zinc oxide helps to reduce redness and accelerate healing. This drug is not suitable for active infections and should not be used on open wounds or for intravaginal use. In humid environments like the genital area, it is better to renew it regularly to maintain its protective properties. The short-term and local use of zinc oxide is usually safe, that is why it is used in the process of treating vaginal infections at home.
Positive points
- Creating a protective layer on the skin and preventing the development of inflammation
- Reducing redness and accelerating the healing of surface irritations
- Suitable for urinary or friction burns
Negative points
- Not applicable for active infections
- It should not be used on open wounds or inside the vagina
- It needs regular renewal in the wet area

Triamcinolone ointment for vaginal irritation
The best ointment for vaginal burning in cases where the skin of this area is inflamed and irritated is triamcinolone ointment. This drug belongs to the category of corticosteroids and by inhibiting cellular inflammatory responses, it controls various symptoms such as burning, swelling, itching and redness. The main use of this ointment is limited to the external skin and around the vagina, and its long-term use without a doctor’s supervision may cause the skin to thin or increase local sensitivity. This ointment is not suitable for fungal or bacterial infections and helps to relieve symptoms. Compared to other corticosteroids, triamcinolone ointment is more effective and patients have seen results much faster.
Positive points
- Control of burning, itching, swelling and redness caused by inflammation
- Faster onset than other mild corticosteroids
- Suitable for the external skin of the vagina
Negative points
- Long-term use without medical supervision can cause thinning of the skin
- Not suitable for fungal or bacterial infections
- It is only used to relieve inflammatory symptoms

Clotrimazole ointment for vaginal irritation
Clotrimazole ointment is one of the most widely used drugs for the treatment of vaginal fungal infections. By stopping the growth of yeast, which is the cause of fungal infection, this medicine inhibits their growth and reproduction and reduces itching, burning and abnormal secretions in the vagina. Clotrimazole is only suitable for infectious cases and is not useful for non-infectious inflammations. This ointment has a greater local effect on vaginal infections with its high penetrating power. Clotrimazole is usually prescribed topically on the external area of the vagina or with an applicator, and it is necessary to complete the course of treatment with it to prevent the recurrence of infection. Excessive use of clotrimazole ointment can cause local irritation, so it is very important to follow the doctor’s order when using it.
Positive points
- Inhibiting the growth of fungi and treating vaginal fungal infections
- Reducing itching, burning and abnormal secretions
- High local penetrating power
Negative points
- It is not used for non-infectious inflammations
- Excessive use may cause local irritation
Topical estrogen ointment for vaginal irritation
Many women experience vaginal dryness and burning as they age or decrease the level of estrogen hormones. Topical estrogen ointment can restore the vaginal tissue by increasing the moisture of the genital area and the thickness of the mucus, and reduce the itching and burning caused by the lack of hormones. This ointment has little systemic effect and is mostly limited to the place of use; This also makes them have less side effects than oral drugs. The use of estrogen ointment is usually recommended for short periods under the supervision of a doctor to maintain hormonal balance. Topical estrogen is not used for fungal or bacterial infections and focuses on relieving dryness and reducing sensitivity and irritation caused by hormonal changes.
Positive points
- Increased moisture and thickness of vaginal mucus
- Reducing dryness, itching and burning caused by hormone deficiency
- Low systemic effect and fewer side effects than oral drugs
Negative points
- It is not used for fungal or bacterial infections
- Long-term use is not recommended without a doctor’s advice
- Only suitable for hormonal problems and dryness
Clindamycin ointment for vaginal needle
In cases where vaginal burning is caused by bacterial infections, especially vaginal bacteriosis, clindamycin ointment is considered a good treatment option. This topical antibiotic controls the growth of harmful microbes by inhibiting protein synthesis needed by bacteria and reduces inflammation caused by infection. Clindamycin is not suitable for fungal infections and is only used in bacterial conditions. This ointment is also used for a short period and locally on the vaginal area, and it is very important to fully comply with its treatment period. During the use of clindamycin ointment, it is necessary to pay attention to any skin irritation or sensitivity, and if any unusual symptoms occur, the doctor should be notified. To get to know Read our article about the best pill for uterine infection.
Positive points
- Controlling the growth of harmful bacteria and reducing inflammation caused by vaginal bacteriosis
- Effective for external bacterial infections
- Short-term and local use
Negative points
- Not suitable for fungal infections
- It is only used in bacterial conditions
- The need to fully comply with the treatment period to prevent the recurrence of infection
How to use ointment for vaginal burning

In order to be able to get the best ointment for vaginal burning, you must follow a few points when using it. In addition to making the medicine more effective, these cases also prevent the occurrence of allergy and re-infection.
- Before anything else, wash your hands well with soap and water and dry them
- Wash the affected area gently with lukewarm water without using perfumed detergents such as a suitable hygiene gel.
- Apply a small amount of ointment on the external area of the vagina according to the doctor’s instructions.
- If needed and if the doctor had prescribed it for you, you can use the applicator to do this for the internal area as well.
- It is better to use the ointment at night before going to bed so that the medicine has enough time to be absorbed.
- Avoid wearing tight or non-cotton underwear during the treatment period, as heat and humidity create the perfect environment for fungi and bacteria to grow.
Regular and complete use of the drug will help prevent the recurrence of burning and inflammation of the vaginal area, even after the symptoms have subsided.
Source: Digikala Mag
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