Researchers discovered new findings by dissecting the brains of Alzheimer’s patients

Researchers have examined the brain tissues of people with Alzheimer’s in autopsies and obtained new data about how the immune cells in the brain of these people.

According to Tekna’s technology and technology news service, the immune cells in the brains of Alzheimer’s sufferers have different functions compared to normal and healthy people. For this reason, researchers believe that this factor can be effective in the occurrence and development of this disease.

According to a report published by Science Alert, Washington University researchers have conducted a study on this disease. They found that the microglia immune cell in the brain of sick people was in a pro-inflammatory state most of the time compared to healthy people, and this could cause the defense abilities of this part to fail.

The autopsies of 12 people with Alzheimer’s and 10 healthy people showed that their brain tissues differed from each other in terms of microglia genes. With the help of the new method, the researchers were able to perform single nuclear RNA sequencing in the brains of these people and succeeded in identifying 10 different clusters of microglia in the brains of the patients.

These microglia cells in the brains of patients were probably not able to perform defensive activity as well. They cannot remove dead cells or remove waste. Researchers believe that microglia can change over time and its type cannot be known just by examining a person’s brain. According to the researchers, the brains of these people should be monitored over time and the progress of Alzheimer’s disease and the role of microglia should be monitored by examining these cells.